{"id":542,"date":"2016-09-26T15:28:08","date_gmt":"2016-09-26T11:58:08","guid":{"rendered":"http:\/\/ebnsinagenelab.com\/?page_id=542"},"modified":"2016-09-27T09:43:42","modified_gmt":"2016-09-27T06:13:42","slug":"%d8%af%da%a9%d8%aa%d8%b1-%d8%b3%db%8c%d9%85%d8%a7-%d9%85%d9%86%d8%b5%d9%88%d8%b1%db%8c-%d8%af%d8%b1%d8%ae%d8%b4%d8%a7%d9%86","status":"publish","type":"page","link":"https:\/\/ebnsinagenelab.com\/?page_id=542","title":{"rendered":"\u0631\u0632\u0648\u0645\u0647 \u062f\u06a9\u062a\u0631 \u0633\u06cc\u0645\u0627 \u0645\u0646\u0635\u0648\u0631\u06cc \u062f\u0631\u062e\u0634\u0627\u0646"},"content":{"rendered":"
\"\u062f\u06a9\u062a\u0631

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\n

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\n
\n

Curriculum Vitae<\/strong><\/h2>\n

 <\/p>\n

Dr Sima Mansoori Derakhshan, M.D, Ph.D<\/strong>
\n Associated Professor of Medical Genetics<\/strong><\/h5>\n

Department of Medical Genetics
\nFaculty of Medicine
\nTabriz University of Medical Sciences
\nAttar Nishabori Road
\nGolgasht Tabriz
\nPost code: 51664-14776, Iran
\nTel\/Fax: +98 (411) 3364666
\nMobile:09141779918
\nEmail: mansooris@tbzmed.ac.ir
\nmderakhshan2002@gmail.com<\/p>\n

\n
EDUCATION<\/strong><\/h5>\n
\n

Sep 2010\u2013March 2011<\/em> <\/span><\/p>\n

Tabriz University of Medical Sciences<\/strong>
\n Education and Development Center<\/strong>
\n Tabriz, Iran<\/strong>
\nFellowship in Academic Skills
\nConsisting: Educational management and planning,educational counseling, program evaluation, teaching and research methodology; and student assessment<\/p>\n

Jan 2004 \u2013 Feb 2008<\/span> <\/em><\/p>\n

University of Melbourne<\/strong>
\n Faculty of Medicine, Dentistry and Health Sciences<\/strong>
\n Paediatrics Department<\/strong>
\n Murdoch Children’s Research Institute<\/strong>
\n Cell and Gene Therapy Group<\/strong>
\n Melbourne_Australia<\/strong>
\nPh.D in Genetics
\nThesis title: Antisense therapy for IVSI-110 mutation in \u03b2-thalassemia
\nThis study aims to provide a gene therapy strategy for \u03b2-thalassemia.<\/p>\n

Feb 2006 \u2013 Feb 2007 <\/em><\/span><\/p>\n

University of Melbourne<\/strong>
\n Faculty of Medicine, Dentistry and Health Sciences<\/strong>
\n Paediatrics Department<\/strong>
\n Murdoch Children’s Research Institute<\/strong>
\n Melbourne_Australia<\/strong>
\nGraduate Diploma in Genetic Counceling<\/p>\n

Oct 1991 \u2013 Jul 1998<\/span> <\/em><\/p>\n

Tabriz University of Medical Sciences<\/strong>
\n Tabriz_ IRAN<\/strong>
\nMedical Doctor (MD)
\n\u06f1\u066b Thesis title: Retrospective study on side effects of cataract surgery in 50 diabetic patients in Nicoucari hospital in 1997<\/p>\n

\n
WORK HISTORY<\/strong><\/h5>\n
\n

\u06f2\u06f0\u06f0\u06f8-Now<\/em> <\/span><\/p>\n

Academic Staff<\/strong><\/span>
\nDepartment of Medical Genetics
\nFaculty of Medicine
\nTabriz University of Medical Sciences & Health Services
\nAttar Nishabori Road
\nGolgasht, Post code: 5166614711
\nTabriz, Iran<\/p>\n

\u06f2\u06f0\u06f0\u06f9-Now<\/em> <\/span><\/p>\n

Director of Ebne Sina Medical Genetic Centre<\/strong><\/span>
\nSpecialized and Sub specialized Outpatient Clinic of Tabriz Medical Science University
\nSheikh Alraeis Clinic, Azadi Ave, Tabriz, Iran.<\/p>\n

\u06f2\u06f0\u06f0\u06f7-\u06f2\u06f0\u06f0\u06f8<\/em> <\/span><\/p>\n

Research assistant<\/strong><\/span>
\nMurdoch Children’s Research Institute
\nCell and Gene Therapy Group
\nMelbourne, Australia<\/p>\n

Responsibilities:
\nWorking in gene therapy in \u03b2-thalassemia projects<\/p>\n

\u06f2\u06f0\u06f0\u06f1-\u06f2\u06f0\u06f0\u06f4<\/span><\/em><\/p>\n

Head of Urban health center<\/strong><\/span>
\nTabriz, East Azerbaijan
\nIRAN<\/p>\n

\u06f1\u06f9\u06f9\u06f9-\u06f2\u06f0\u06f0\u06f1<\/span><\/em><\/p>\n

Thalassaemia coordinator in health centre<\/strong><\/span>
\nBonab Health center
\nBonab, East Azarbaijan
\nIRAN<\/p>\n

\u06f1\u06f9\u06f9\u06f8-\u06f2\u06f0\u06f0\u06f1<\/span> <\/em><\/p>\n

General physician in emergency unit<\/strong><\/span>
\nImam Khomeini Hospital- Bonab
\nEast Azerbaijan
\nIRAN<\/p>\n

\u06f1\u06f9\u06f9\u06f8-\u06f2\u06f0\u06f0\u06f1<\/span><\/em><\/p>\n

Head of Urban health center<\/strong><\/span>
\nBonab, East Azerbaijan
\nIRAN<\/p>\n

\n
PUBLICATIONS<\/strong><\/h5>\n
\n

\u06f1\u066b Jim Vadales, Mikhail nefedov, Hady wardan, Sima Mansoori derakhshan<\/span><\/strong>, Lucille Voullaire, Duangporn Jamsai, Robert Williamson and Pannayiotis A Ioannou. Humanised mouse model containting the common IVS1-110 splicing mutation. The journal of Biological Chemistry , 2006, 281 ( 11): 7399-7405<\/p>\n

\u06f2\u066b A.G. Behbahan, B. Poorshiri, F. Mortazavi, M.S. Khaniani and S.M. Derakhshan<\/strong><\/span>. NPHS1 Gene Mutations in Children with Nephrotic Syndrome in Northwest Iran. Pakistan Journal of Biological Sciences 16 (17): 882-886, 2013.<\/p>\n

\u06f3\u066b Ebrahimi Ammar, khaniani S Mahmoud, Mansoori Derakhshan Sima<\/span><\/strong>. Stable expression of modified Gene encoding functional Human coagulation Factor VIII. Journal For Drugs and medicines Vol 3 (2), October, 2011, pp. 19-25.<\/p>\n

\u06f4\u066b Iamal Mohmmadian. Sima Mansoori Derakhshan<\/span><\/strong>, Masood Mohmmadian, Mahmoud Shekari Khaniani. Construction of Yeast Recombinant Expression Vector Containing Human Epidermal Growth Factor (hEGF). Advanced Pharmaceutical Bulletin: 2013;3(2), 473-476
\n\u06f5\u066b Behrooz Farhadi, Mahmoud Shekari Khaniani, Sima Mansoori Derakhshan<\/span><\/strong>\uf02a. Construction of pPIC9 Recombinant Vector Containing Human Stem Cell Factor, Advanced Pharmaceutical Bulletin: 2013;3(2), 303-308.<\/p>\n

\u06f6\u066b Salman Asghari, Mahmoud Shekari Khaniani, Masood Darabei, Sima Mansoori Derakhshan\uf02a<\/span><\/strong>. Cloning of Soluble Human Stem Cell Factor in pET-26b(+) vector, Advanced Pharmaceutical Bulletin,2014,4(1),91-95.<\/p>\n

\u06f7\u066b Sima Mansoori Derakhshan<\/span><\/strong>, Shamsei Abbasalizadeh, Fatemeh Abbasalizadeh, Mahmoud Shekari Khaniani Pernatal Diagnosis of Spinal Muscular Atrophy: Clinical experience and Molecular genetics of SMN gene analysis in 36 cases, Journal of Prenatal Medicine 2013, 7 (3): 32-34<\/p>\n

\u06f8\u066b Mahmoud Shekari Khaniani, Sima Mansoori Derakhshan\uf02a<\/span><\/strong>. Molecular Characterisation and Assessment of Clinical Significance of Small Fragile X Alleles. Journal of Anlytical Reasarch in Clincal Medicine (2013, Vol 1, No 1 pp 2-17)<\/p>\n

\u06f9\u066b Fatemeh Afkhamei, Mahmoud Shekari Khaniani , Layia Farzadei, Zynab Paknejade, Sima Mansoori Derakhshan\uf02a<\/span><\/strong>. The HLA- G 14bp insertion\/delation polymorphisim in women with recurrent spontaneous abortion, Iranian Journal of Allergy, Asthma and Immunology. October 2014; 13 (5): 364-369.<\/p>\n

\u06f1\u06f0\u066b Tamochine Moramei, Abbas Ali Hossainpour feize, Sima Mansoori Derakhshan<\/span><\/strong>, Mahmoud Shekari khaniani. Detection of Haemophilia A carriers in Azeri Turkish Population of Iran: Usefulness of HindIII and BclI markers, Clin Appl Thromb Hemost. 2015 Nov;21(8):755-9.<\/p>\n

\u06f1\u06f1\u066b Nasrin Sohrabi, Mahmoud Shekari Khaniani, Sima Mansoori Derakhshan\uf02a<\/span><\/strong>. Evaluation of Association Between HLA Class II DR4\u2013DQ8 Haplotype and Type I Diabetes Mellitus in Children of East Azerbaijan State of Iran, Adv Pharm Bull, 2015 Mar, 5(1): 137\u2013\u06f1\u06f4\u06f0\u066b<\/p>\n

\u06f1\u06f2\u066b Nahid Karimian Fathi; Mahmood Shekari Khaniani; Vahid Montazeri, Sima Mansoori Derakhshan\uf02a<\/strong><\/span> Minor role of BRCA2 mutation (Exon2 and Exon11) in patients with early-onset breast cancer amongst Iranian Azeri-Turkish women, Volume 17, Issue 2, February 2014, Page 108-111.<\/p>\n

\u06f1\u06f3\u066b Mahmoud Shekari Khaniani, Nasrin Sohrabi, NedaMansoori Derakhshan, SimaMansoori Derakhshan\uf02a<\/span><\/strong> One Novel Frameshift Mutation on Exon 64 of COL7A1 Gene in an Iranian Individual Suffering Recessive Dystrophic Epidermolysis Bullosa, Annals of Clinical and Laboratory Science, volume 45, # 5 (September \u2013 October) 2015<\/p>\n

\u06f1\u06f4\u066b Samira Goldar, Mahmoud Shekari Khaniani, Sima Mansoori Derakhshan<\/span><\/strong>, Behzad Baradaran. Molecular mechanisms of apoptosis and roles in cancer development and treatment, Journal, VOL, NO: Asian Pacific Journal of Cancer Prevention: APJCP 2015, 16 (6): 2129-44.<\/p>\n

\u06f1\u06f5\u066b Sima Mansoori Derakhshan<\/span><\/strong>, Fatemeh Zeinali Sehrig, Nasrin Sohrabi, Siamak Shiva, Behzad Baradaran, Mahmoud Shekari Khaniani. Evaluation of Association Between HLA Class II DR3\u2013DQ2 Haplotype and Type 1 Diabetes in Children of East Azerbaijan State of Iran, Iran Red Crescent Med J. 2015 Sep; 17(9).<\/p>\n

\u06f1\u06f6\u066b Mahmoud Shekari Khaniani, \u2022 Abdollah Ebrahimi, \u2022 Setareh Daraei, Sima Mansoori Derakhshan<\/strong><\/span>. Genotyping of Intron Inversions and Point Mutations in Exon 14 of the FVIII Gene in Iranian Azeri Turkish Families with Hemophilia A, Indian J Hematol Blood Transfus, DOI 10.1007\/s12288-016-0699-2<\/p>\n

\u06f1\u06f7\u066b Mahmoud Shekari khaniani , Mahdieh Tagizadeh , Abbasali Hosseinpour Feizi Sima Mansoori Derakhshan\uf02a<\/span><\/strong>. Sodium Butyrate and Valproic Acid as Splicing Restoring Agents in Erythroid Cells of \u03b2-Thalassemic Patients. Iran J Biotech. 2016 March;14(1): e1169<\/p>\n

\u06f1\u06f8\u066b Sima Mansoori Derakhshan\uf02a<\/strong><\/span>, Aziz Khorrami, Abbasali Hosseinpour Pour Feizi and Mahmoud Shekari Khaniani. Spectrum of \u03b2-Globin Gene Mutations and \u03b2-Thalassemia Haplotype Analysis among the Iranian Azeri Turkish Population. Epidemiology (sunnyvale) ISSN:2161-1165 ECR, an Open Access,Volume 5, Issue 4, 1000210<\/p>\n

\u06f1\u06f9\u066b Mahmoud Shekari Khaniani,, Aziz Khorrami, Mandana Rafeey, Robabeh Ghergherehchi, Sima Mansoori Derakhshan\uf02a<\/strong><\/span>, MD,Ph.DMolecular Analysis of Glycogen Storage Disease type Ia in Iranian Azeri Turks: Identification of a Novel mutation. JGEN, under press<\/p>\n

\n
CONGRESS PRESENTATIONS: Abstract Published<\/strong><\/h5>\n
\n

\u06f1\u066b \u06f3th International and 18th Natinal congress of Iraniani Socity for Reporductive Medicine, Tabriz, Iran, Khaniani M, Derakhshan S, Taghizadeh S, Khoramei A, Mohrramei, T., 2012 April<\/p>\n

\u06f2\u066b First International congress of Molecular and cellular Medicine. Bahan 1389, Shiraz, Iran, Ebrahimi A, Shekari Khaniani M, Mansoori Derakhshan S, Moharramei T<\/p>\n

\u06f3\u066b M. S. Khaniani, S.M. Derakhshan, L Mohammadnejad. Controversy in the mode of inheritance in familial Mediterranean fever diseases, Molecular analysis of MEFV gene in patients. European Human Genetics conference, Nirenberg, Germany. 2012, June.
\n\u06f4\u066b S.M. Derakhshan, M. S. Khaniani, Tagizadeh, Sodium Butyrate and Valproic acid as splicing restoring agents in erythroid cells of b-thalassemia patients. European Human Genetics conference, Nirenberg, Germany. 2012, June.<\/p>\n

\u06f5\u066b M. S. Khaniani, S.M. Derakhshan. To characterize and analyze the haplotype of Normal and “at risk of expansion” FMR1 CGG repeat alleles. European Human Genetics conference, Nirenberg, Germany. 2012, June.<\/p>\n

\u06f6\u066b Sima Mansoori Derakhshan & Jim Vadoles. 10th Iranian of Biochestry $ 3th international congress of Biochemistry and Molecular Biology, 2009, Nov<\/p>\n

\u06f7\u066b Sima Mansoori Derakhshan & Jim Vadoles. 10th Iranian of Biochestry $ 3th international congress of Biochemistry and Molecular Biology, 2009, Nov<\/p>\n

\u06f8\u066b M. Shekari Khaniani , S Mansoori Derakhshan<\/span><\/strong>. 6th International Congress of Multiple Sclerosis in Iran, Tabriz, Mehr 1388<\/p>\n

\u06f9\u066b M. S. Khaniani, S.M. Derakhshan<\/strong><\/span>, S. Tagezadeh, M, Zyadei, M, Nyosha. New aspect of fragile X mental retardation 1 (FMR1) gene. The Second Iranian Medical Genetics Congress. Khordad, 1390<\/p>\n

\u06f1\u06f0\u066b M. S. Khaniani, S.M. Derakhshan<\/span><\/strong>. Inhibition of aberrant splicing of IVS-110 \uf062-globin pre-mRNA by antisese oligonucleotide. The Second Iranian Medical Genetics Congress. Khordad, 1390<\/p>\n

\u06f1\u06f1\u066b M. S. Khaniani, S.M. Derakhshan<\/strong><\/span>, L. Mohmmadnejade, M, Hajalilo, A. Mallekiyan, Y. Moaddabe. Molecular analysis of MEFVgene in Iranian patients with famimlial meditaranian fevere. The Second Iranian Medical Genetics Congress. Khordad, 1390<\/p>\n

\u06f1\u06f2\u066b M. S. Khaniani, S.M. Derakhshan<\/strong><\/span> A. pourfeizi, A. Kazemei. An Improved diagnostic PCR assay for detection of \uf061-thalassemia detection and \uf061-triplication by multiplex PCR.The Second Iranian Medical Genetics Congress. Khordad, 1390<\/p>\n

\u06f1\u06f3\u066b M. S. Khaniani, S.M. Derakhshan<\/strong><\/span>, A. pourfeizi A, Kazemei. Eritroid progenitor cells expanded from bone marrow: molecular characterisation and fuctional competence. The Second Iranian Medical Genetics Congress. Khordad, 1390<\/p>\n

\u06f1\u06f4\u066b S Mansoori Derakhshan<\/span><\/strong>, M. ziadi, A. Hosseinpour Feizi, M. Shekari khaniani. Singapor. Molecular study of alpha thalassemia deletion and non deletional mutation frquency in alpha globin locus among potential carriers in North West of Iran. 2012 Apri<\/p>\n

\u06f1\u06f5\u066b Nahid karimian fahi, mahmoud Shekari Khaniani, Vahid Motazeri, Sima Mansoori derakhshan<\/span><\/strong> . Minor role of BRCA2 mutation (Exon2 and Exon11) in patients with early-onset breast cancer amongst Iranian Azeri-Turkish women. 8th international congress of cancer. Tehran, Esfand 1391<\/strong><\/p>\n

\u06f1\u06f6\u066b M. S. Khaniani, S.M. Derakhshan, Z. Garadagchei, 3rd Iranian Medical Genetics Congress. Ordibehesht, 1391<\/p>\n

\u06f1\u06f7\u066b S.Mansoori Derakhshan, Akbar Jalili, M. Shekari Khaniani, Sorayya Shiri torkamani, Soghra Taghizadeh. Frequency of G6PC gene mutations in GSD1a patients from North West of Iran. 3rd Iranian Medical Genetics Congress. Ordibehesht, 1391<\/p>\n

\u06f1\u06f8\u066b M. Shekari. Khaniani, S.Mansoori Derakhshan, Akbar Jalili, Sorayya Shiri torkamani, Soghra Taghizadeh. GJB2 mutation spectrum in 450 Iranian Azeri Turkish patients with nonsyndromic hearing impairment. 3rd Iranian Medical Genetics Congress. Ordibehesht, 1391<\/p>\n

\u06f1\u06f9\u066b M. Shekari. Khaniani, S.Mansoori Derakhshan, Akbar Jalili, Sorayya Shiri torkamani, Soghra Taghizadeh. The spectrum of mutations in the phenylalanine hydroxylase gene in patients with phenylketonuria North West Iran. 3rd Iranian Medical Genetics Congress. Ordibehesht, 1391<\/p>\n

\u06f2\u06f0\u066b M. Shekari Khaniani S.Mansoori Derakhshan, Soghra Taghizadeh, A Jalili, Sorayya Shiri torkamani. \u03b2-globin Frameworks in \u03b2-Thalassemia carriers from Northwest of Iran 3rd Iranian Medical Genetics Congress. Ordibehesht, 1391<\/p>\n

\u06f2\u06f1\u066b S.Mansoori Derakhshan, M. Shekari Khaniani, F. Zynali Sohrag. Evaluation of Association between HLA Class II DR3\u2013DQ2 Haplotype and Type 1 Diabetes in Children of East Azerbaijan State of Iran. 3rd Iranian Medical Genetics Congress. Ordibehesht, 1391<\/p>\n

\u06f2\u06f2\u066b S.Mansoori Derakhshan, M. Shekari Khaniani, S Daraii. \u03b2-globin Frameworks in \u03b2-Thalassemia carriers from Northwest of Iran. 3rd Iranian Medical Genetics Congress. Ordibehesht, 1391<\/p>\n

\u06f2\u06f3\u066b Z. Garadagchei, S.Mansoori Derakhshan M. Ghojazadeh, M. Shekari. Khaniani. The 21th Iranian Congress of Physiology and Pharmacology, 23-27 August 2013<\/p>\n

\u06f2\u06f4\u066b N. Sohrabei, Zeinali Sehrig, M. Shekari Khaniani, S. Shiva, B Baradaran, S.Mansoori Derakhshan. The 21th Iranian Congress of Physiology and Pharmacology, 23-27 August 2013<\/p>\n

\u06f2\u06f5\u066b European Human Genetics conference: 2007\/Nice\/france<\/p>\n

\u06f2\u06f6\u066b \u06f1\u06f1th international congress of Human Genetics: 2006\/ Brisbane\/ Australia<\/p>\n

\u06f2\u06f7\u066b \u06f1\u06f0th International conference on Thalassaemia and Haemoglobinopathi and12th Intenernational TIF conference for thalassaemia Patients and Parents: 2006\/ Dobai\/ UAE<\/p>\n

\u06f2\u06f8\u066b \u06f5th Australian Gene therapy Society Meeting: 2007\/ Melbourne\/ Austra<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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